POOR GLYCEMIC CONTROL AND THE RISK OF DIABETIC PERIPHERAL NEUROPATHY AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS
Keywords:
Diabetic Peripheral Neuropathy, Glycemic Control, HbA1c, Type 2 Diabetes Mellitus, NeuropathyAbstract
Type 2 Diabetes Mellitus (T2DM) is a growing global health problem associated with various chronic complications, including diabetic peripheral neuropathy (DPN). DPN is one of the most common microvascular complications that may lead to pain, foot ulcers, amputation, and reduced quality of life. Poor glycemic control has been identified as an important modifiable risk factor for DPN; however, evidence from Indonesia remains limited. This study aimed to analyze the association between poor glycemic control and diabetic peripheral neuropathy among patients with type 2 diabetes mellitus. A descriptive analytic study with a cross-sectional approach was conducted among 390 patients with T2DM in Padang City, Indonesia. Participants were selected using stratified random sampling. Glycemic control was assessed using HbA1c levels, while diabetic peripheral neuropathy was evaluated using the Michigan Neuropathy Screening Instrument (MNSI). Data were analyzed using chi-square tests and multiple logistic regression analysis with a significance level of p < 0.05. The prevalence of diabetic peripheral neuropathy among patients with T2DM was high. Most participants had uncontrolled HbA1c levels, indicating poor glycemic control. Statistical analysis showed a significant association between poor glycemic control and the occurrence of DPN (p < 0.05). Patients with uncontrolled HbA1c levels had a higher risk of developing DPN compared to those with controlled glycemic status. Poor glycemic control was significantly associated with diabetic peripheral neuropathy among patients with type 2 diabetes mellitus. Routine neuropathy screening and optimal glycemic management are essential to prevent complications and improve patient outcomes.
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